Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. This volume in the Methods in Enzymology series comprehensively covers this topic. With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems.
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. This volume in the Methods in Enzymology series comprehensively covers this topic. With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems.
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases, and this volume in the Methods in Enzymology series comprehensively covers this topic
1. Development of inhibitors of PAI-1
Daniel Lawrence
2. Kinetics of Serpin interactions with cofactors and proteases
Steven Olson
3. Fluorescence Correlation Spectroscopy (FCS) or Single molecule
FRET
Anne Gershenson
4. Serpin-enzyme receptors (LRP)
Dudley Strickland
5. Predicting serpin / protease interactions
Jiangning Song
6. Serpins and autophagy
David Perlmutter
7. Plant Serpins
Tom Roberts
8. High throughput Drug discovery
Bibek Gooptu
9. Use of mouse models to study maspin function
Ming Zhang
10. The study of antitrypsin deficiency using animal models
Jeffrey Teckman
11. Use of Mouse Models to study PAI-1
Paul Declerck
12. Production of serpins using cell free systems
Clifford Luke
13. Studying serpin polymerisation in vitro
James Huntington
14. Serpins and neural function
Denis Monard
15. Probing serpin conformational change using mass spectrometry
and related methods
Patrick Wintrode
16. Studying Serpin conformational change
Randy Read
17. Production of serpins in bacteria
Mary Pearce
18. Inhibition of cysteine proteases by serpins
Jan Potempa
19. Post transcriptional regulation of serpins
Rob Medcalf
20. Serpins and the complement system
Rob Pike & Lakshmi Wijeyewickrema
21. Serpins in Caenorhabditis elegans
Stephen Pak & Gary Silverman
22. PEDF and angiogenesis
Patricia Becerra
23. The Serpinb1 knockout mouse
Charaf Benarafa
24. Biophysical approaches to studying serpin folding
Steve Bottomley
25. TALS for studying the proteases inhibited by Serpins
Chris Overall
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