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Neural Circuit Development ­and Function in the Brain
Comprehensive Developmental Neuroscience
By John Rubenstein, John Rubenstein (Editor In Chief), Pasko Rakic (Editor In Chief)

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Format
Hardback, 848 pages
Other Formats Available

Hardback : £151.00

Published
United States, 1 June 2013

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms.


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Product Description

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms.

Product Details
EAN
9780123972675
ISBN
0123972671
Other Information
Illustrated
Dimensions
28.3 x 22 x 4.4 centimeters (2.54 kg)

Promotional Information

Part of a series offering the most comprehensive coverage of developmental neuroscience available, covering molecular development through to cognition and disease

Table of Contents

I: Circuit Development
1. The Form and Functions of Neural Circuits in the Olfactory Bulb
G. Lepousez, P.-M. Lledo
2. Functional Circuit Development in the Auditory System
D.B. Polley, A.H. Seidl, Y. Wang, J.T. Sanchez
3. Development of the Superior Colliculus/Optic Tectum
B.E. Stein, T.R. Stanford
4. Multisensory Circuits
A.J. King
5. Cerebellar Circuits
M. Kano, M. Watanabe
6. Dendritic Spines
D. Muller, I. Nikonenko
7. Cortical Columns
Z. Molnár
8. Neonatal Cortical Rhythms
R. Khazipov, M. Colonnese, M. Minlebaev
9. Spike Timing-Dependent Plasticity
D.E. Shulz, D.E. Feldman

II: Cognitive Development
10. Introduction to Cognitive Development from a Neuroscience Perspective
H. Tager-Flusberg
11. Theories in Developmental Cognitive Neuroscience
M.H. Johnson
12. Structural Brain Development: Birth Through Adolescence
J.B. Colby, E.D. O'Hare, J.E. Bramen, E.R. Sowell
13. Statistical Learning Mechanisms in Infancy
J. Lany, J.R. Saffran
14. Development of the Visual System
S.P. Johnson
15. The Development of Visuospatial Processing
J. Stiles, N. Akshoomoff, F. Haist
16. Memory Development
P.J. Bauer
17. Early Development of Speech and Language: Cognitive, Behavioral, and Neural Systems
H. Tager-Flusberg, A.M. Seery
18. The Neural Architecture and Developmental Course of Face Processing
G. Righi, C.A. Nelson III
19. Developmental Neuroscience of Social Perception
A. Voos, C. Cordeaux, J. Tirrell, K. Pelphrey
20. Developmental Cognitive Neuroscience of Theory of Mind
H. Gweon, R. Saxe
21. A Neuroscience Perspective on Empathy and Its Development
J. Decety, K.J. Michalska
22. Developing Attention and Self-Regulation in Infancy and Childhood
M.I. Posner, M.K. Rothbart, M.R. Rueda
23. The Neural Correlates of Cognitive Control and the Development of Social Behavior
A. Lahat, N.A. Fox
24. Executive Function: Development, Individual Differences, and Clinical Insights
C. Hughes
25. The Effects of Stress on Early Brain and Behavioral Development
M.R. Gunnar, E.P. Davis
26. Sex Differences in Brain and Behavioral Development
A.M. Beltz, J.E.O. Blakemore, S.A. Berenbaum

III: Diseases
27. Neural-Tube Defects
C. Pyrgaki, L. Niswander
28. Fetal Alcohol Spectrum Disorder: Targeted Effects of Ethanol on Cell Proliferation and Survival
S.M. Mooney, P.J. Lein, M.W. Miller
29. Azetidine-2-Carboxylic Acid and Other Nonprotein Amino Acids in the Pathogenesis of Neurodevelopmental Disorders
E. Rubenstein
30. Down Syndrome
A.B. Bowman, K.C. Ess, K.K. Kumar, K.L. Summar
31. Lissencephalies and Axon Guidance Disorders
E.H. Sherr, L. Fernandez
32. Developmental Disabilities, Autism, and Schizophrenia at a Single Locus: Complex Gene Regulation and Genomic Instability of 15q11–q13 Cause a Range of Neurodevelopmental Disorders
N. Urraca, L.T. Reiter
33. Fragile X Clinical Features and Neurobiology
M.J. Leigh, R.J. Hagerman
34. Autisms
M. Persico
35. Neurodevelopmental Genomics of Autism, Schizophrenia, and Related Disorders
J.F. Cubells, D. Moreno-De-Luca
36. Excitation–Inhibition Epilepsies
A.X. Thomas, A.R. Brooks-Kayal
37. Sensory Organ Disorders (Retina, Auditory, Olfactory, Gustatory)
D.C. Gillespie
38. The Developmental Neurobiology of Repetitive Behavior
S.-J. Kim, M. Lewis, J. Veenstra-VanderWeele
39. Disorders of Cognitive Control
B.J. Casey, N. Franklin, M.M. Cohen
40. Language Impairment
R.H. Fitch
Index

About the Author

Dr. Rubenstein is a Professor in the Department of Psychiatry at the University of California, San Francisco. He also serves as a Nina Ireland Distinguished Professor in Child Psychiatry at the Nina Ireland Laboratory of Developmental Neurobiology. His research focuses on the regulatory genes that orchestrate development of the forebrain. Dr. Rubenstein's lab has demonstrated the role of specific genes in regulating neuronal specification, differentiation, migration and axon growth during embryonic development and on through adult life. His work may help to explain some of the mechanisms underlying human neurodevelopmental disorders such as autism. Dr. Rakic is currently at the Yale School of Medicine, Department of Neuroscience, where his main research interest is in the development and evolution of the human brain. After obtaining his MD from the University of Belgrade School of Medicine, his research career began in 1962 with a Fulbright Fellowship at Harvard University after which he obtained his graduate degrees in Developmental Biology and Genetics. He held a faculty position at Harvard Medical School for 8 years prior to moving to Yale University, where he founded and served as Chair of the Department of Neurobiology for 37 years, and also founder and director of the Kavli Institute for Neuroscience. In 2015, he returned to work full-time on his research projects, funded by US Public Health Services and various private foundations.

He is well known for his studies of the development and evolution of the brain, in particular his discovery of basic cellular and molecular mechanisms of proliferation and migration of neurons in the cerebral cortex. He was president of the Society for Neuroscience and popularized this field with numerous lectures given in over 35 counties. In 2008, Rakic shared the inaugural Kavli Prize in Neuroscience with Thomas Jessell and Stan Grillner. He is currently the Dorys McConell Duberg Professor of Neuroscience and serves on Advisory Boards and Scientific Councils of a number of Institutions and Research Foundations.

Reviews

"This is a comprehensive and information-packed book on neural circuit development and function. There have been tremendous advances over the past several years in understanding brain function as it relates to structure, but this information has not been easily accessible by clinicians and researchers. This book, written and edited by outstanding researchers in the field, provides this important information in an organized and relevant fashion… I highly recommend it." Rating: 3 Stars --Doody.com, January 17, 2014

"This is the third of a three volume series that is intended to summarize the current state of developmental neuroscience. There are three sections with Rubenstein and Rakic as chief editors and each section having a section editor tasked with peer reviewing the articles therein." --Reference & Research Book News, December 2013

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