Im Rahmen der Meta-Analyse wird versucht, die in klinischen Versuchen gesammelten Daten zu kombinieren, um Schlußfolgerungen über die Wirksamkeit einer Behandlung abzuleiten. Das Thema ist daher gleichermaßen relevant für Medizin und pharmazeutische Industrie. Einschlägige methodische Ansätze werden kritisch diskutiert und miteinander verglichen. Nützlich sind die ausführlichen Hinweise auf weiterführende Literatur zu Spezialthemen. (10/00)
PART A: META-ANALYSIS METHODOLOGY: THE BASICS Introduction: Meta-analysis: Its Development and Uses Defining Outcome Measures used for Combining via Meta-analysis Random Effects Models for Combining Study Estimates Exploring Between Study Heterogeneity Publication Bias Study Quality Sensitivity Analysis Reporting the Results of a Meta-analysis Fixed Effects Methods for Combining Study Estimates PART B: ADVANCED AND SPECIALIZED META-ANALYSIS TOPICS Bayesian Methods in Meta-analysis Meta Regression Meta-analysis of Different Types of Data Incorporating Study Quality into a Meta-analysis Meta-analysis of Multiple and Correlated Outcome Measures Meta-analysis of Epidemiological and other Observational Studies Generalised Synthesis of Evidence - Combining Different Sources of Evidence Meta-analysis of Survival Data Cumulative Meta-analysis Miscellaneous and Developing Areas of Applications in Meta-Analysis Appendix I: Software Used for the Examples in this Book
Show moreIm Rahmen der Meta-Analyse wird versucht, die in klinischen Versuchen gesammelten Daten zu kombinieren, um Schlußfolgerungen über die Wirksamkeit einer Behandlung abzuleiten. Das Thema ist daher gleichermaßen relevant für Medizin und pharmazeutische Industrie. Einschlägige methodische Ansätze werden kritisch diskutiert und miteinander verglichen. Nützlich sind die ausführlichen Hinweise auf weiterführende Literatur zu Spezialthemen. (10/00)
PART A: META-ANALYSIS METHODOLOGY: THE BASICS Introduction: Meta-analysis: Its Development and Uses Defining Outcome Measures used for Combining via Meta-analysis Random Effects Models for Combining Study Estimates Exploring Between Study Heterogeneity Publication Bias Study Quality Sensitivity Analysis Reporting the Results of a Meta-analysis Fixed Effects Methods for Combining Study Estimates PART B: ADVANCED AND SPECIALIZED META-ANALYSIS TOPICS Bayesian Methods in Meta-analysis Meta Regression Meta-analysis of Different Types of Data Incorporating Study Quality into a Meta-analysis Meta-analysis of Multiple and Correlated Outcome Measures Meta-analysis of Epidemiological and other Observational Studies Generalised Synthesis of Evidence - Combining Different Sources of Evidence Meta-analysis of Survival Data Cumulative Meta-analysis Miscellaneous and Developing Areas of Applications in Meta-Analysis Appendix I: Software Used for the Examples in this Book
Show morePART A: META-ANALYSIS METHODOLOGY: THE BASICS Introduction:
Meta-analysis: Its Development and Uses Defining Outcome Measures
used for Combining via Meta-analysis Random Effects Models for
Combining Study Estimates Exploring Between Study Heterogeneity
Publication Bias Study Quality Sensitivity Analysis Reporting the
Results of a Meta-analysis Fixed Effects Methods for Combining
Study Estimates PART B: ADVANCED AND SPECIALIZED META-ANALYSIS
TOPICS Bayesian Methods in Meta-analysis Meta Regression
Meta-analysis of Different Types of Data Incorporating Study
Quality into a Meta-analysis Meta-analysis of Multiple and
Correlated Outcome Measures Meta-analysis of Epidemiological and
other Observational Studies Generalised Synthesis of Evidence -
Combining Different Sources of Evidence Meta-analysis of Survival
Data Cumulative Meta-analysis Miscellaneous and Developing Areas of
Applications in Meta-Analysis Appendix I: Software Used for the
Examples in this Book
Alex Sutton has published extensively on meta-analysis methodology generally, and on publication bias specifically in recent years, including a major systematic review on the topic of the methodology that has been developed for meta-analysis. He currently has an active interest in the area of partially reported study information, which is currently under-researched. Dr. Sutton is co-author of a textbook on metaanalysis (Methods for Meta Analysis in Medical Research), which was published by Wiley in 2000.
“Both books can be recommended for graduate training and are useful additions to the library of those interested in the meta-analytic accumulation of literatures on training, vocational learning, and education in the professions.” (Vocations and Learning, 15 December 2010) "This well-written book offers an exhaustive criticism and up-to-date references, illustrates effectively with real life examples and data…" (Journal of Statistical Computation & Simulation, July 2004) "this is an excellent book..." (Short Book Reviews, April 2001) "...recommended for mathematically skilled readers interested in getting an overview of the various methods and the existing literature..." (Statistics in Medicine, 15 October 2003)
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