Hardback : £132.00
This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad
understanding is essential for translation of laboratory findings into the clinic.
Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to
the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic
events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of the popular book will serve as a text for both undergraduate and postgraduate
use and also as an introduction for clinicians and scientists new to the field.
This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad
understanding is essential for translation of laboratory findings into the clinic.
Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to
the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic
events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of the popular book will serve as a text for both undergraduate and postgraduate
use and also as an introduction for clinicians and scientists new to the field.
1: L.M. Franks and Margaret A. Knowles: What is cancer?
2: Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane
Green, Emily Banks, and Timothy J. Key: The causes of cancer
3: D. Timothy Bishop: Inherited susceptibility to cancer
4: Beate Köberle, John P. Wittschieben, and Richard D. Wood: DNA
repair and cancer
5: Jonathan C. Cheng and Peter A. Jones: Epigenetic events in
cancer
6: Denise Sheer and Janet Shipley: Molecular cytogenetics of
cancer
7: Margaret A. Knowles: Oncogenes
8: Sonia Lain and David P. Lane: Tumour suppressor genes
9: Chris J. Norbury: The cancer cell cycle
10: Robert F. Newbold: Cellular immortalization and telomerase
activation in cancer
11: Sally A. Prigent: Growth factors and their signalling pathways
in cancer
12: Dean A. Fennell: Apoptosis: molecular physiology and
significance for cancer therapeutics
13: Paul Farrell: Mechanisms of viral carcinogenesis
14: Peter W. Szlosarek and Frances R. Balkwill: Cytokines and
cancer
15: Charlotte L. Bevan: Hormones and cancer
16: Ian Hart: The spread of tumours
17: K.Tahtis and R.Bicknell: Angiogenesis
18: Mel Greaves: Stem cells, heamopoiesis, and leukaemia
19: Jos Jonkers and Anton Berns: Animal models of cancer
20: Peter C. L. Beverley: The immunology of cancer
21: Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R.
Lemoine: The molecular pathology of cancer
22: Silvana Debernardi, Rachel Craven, Bryan D. Young, and
Rosamonde E. Banks: From transcriptome to proteome
23: Ian S. Fentiman: Local treatment of cancer
24: D.R. Camidge and D.I. Jodrell: Chemotherapy
25: Anne Kiltie: Radiotherapy and molecular radiotherapy
26: T. Geldart, M.J. Glennie, and P.W.M. Johnson: Monoclonal
antibodies and therapy
27: Andrew M. Jackson and Joanne Porte: Immunotherapy of cancer
28: John David Chester: Cancer gene therapy
29: Peter Sasieni and Jack Cuzick: Screening
30: Peter Selby and Margaret A Knowles: Conclusions and prospects
Margaret Knowles is Professor of Experimental Cancer Research at the University of Leeds, and Associate Director of the Cancer Research UK Clinical Centre, also in Leeds. Peter Selby is Professor of Cancer Medicine and Director of the National Cancer Research Network at the University of Leeds.
`Review from previous edition This edition is highly recommended to
students of cancer, whether they be medical or non-medical
scientists, and will take its readers to the leading edge of cancer
research ... admirable book.'
The Bulletin of the Royal College of Pathologists
`Successive editions of this book have mirrored developments in
cancer research and this new edition continues to provide a short
but comprehensive introduction to the initiation, development and
treatment of cancer.'
ASLIB Book Guide
`The first two editions were good: now it is excellent ...
everything is covered and relevant citations are given. Not only
are important basic clinical and pathological issues covered, but
so too are all the important areas of tumour biology and the
molecular processes and genetics relevant to cancer ... I consider
this an invaluable book ... I intend to advise all my new graduate
students and post docs to buy, read, and study a copy ...
masterfully edited
and well-illustrated text. This book is great! If you are
interested in cancer, buy a copy!'
Peter A. Hall, Journal of Pathology
`This is an excellent book ... As one who teaches cancer genetics
among other things, I greatly welcome a source to which one can
recommend students ... A fascinating read for everyone with an
interest (morbid or not) in the subject.'
Simon Baumberg, Univ. of Leeds, SGM Quarterly
`This is a superb introduction to cancer studies for clinicians and
is difficult to fault ... this must be a bargain hard to beat. I
strongly recommend this text for all involved in cancer studies and
the care of patients with cancer.'
Crispian Scully, Oral Oncology
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