This groundbreaking single-authored textbook equips students with everything they need to know to truly understand the hugely topical field of biomaterials science, including essential background on the clinical necessity of biomaterials, relevant concepts in biology and materials science, comprehensive and up-to-date coverage of all existing clinical and experimental biomaterials, and the fundamental principles of biocompatibility. It features extensive case studies interweaved with theory, from a wide range of clinical disciplines, equipping students with a practical understanding of the phenomena and mechanisms of biomaterials performance; a whole chapter dedicated to the biomaterials industry itself, including guidance on regulations, standards and guidelines, litigation, and ethical issues to prepare students for industry; informative glossaries of key terms, engaging end-of-chapter exercises and up-to-date lists of recommended reading. Drawing on the author's forty years' experience in biomaterials, this is an indispensable resource for students studying these lifesaving technological advances.
David Williams is a Professor at the Wake Forest Institute for Regenerative Medicine, North Carolina, with over forty years' experience in biomaterials science. He is the Editor-in-Chief of the international journal Biomaterials, President of the Tissue Engineering and Regenerative Medicine International Society, TERMIS, and a former Director of the UK Centre for Tissue Engineering, where he is now an Emeritus Professor. In addition to these responsibilities he is a Visiting Professor of the Christiaan Barnard Memorial Hospital, Cape Town, and has travelled extensively to promote excellence in scientific research and writing. He is a Fellow of the Royal Academy of Engineering, and has received numerous awards, including the 2012 Acta Biomaterialia Gold Medal.
1. The clinical necessity of biomaterials in the twenty-first century; 2. Essential materials science; 3. Biocompatibility pathways; 4. Implantable medical devices and artificial organs; 5. Regenerative medicine and tissue engineering; 6. Drug and gene delivery; 7. Imaging and diagnostic systems; 8. Contemporary and future biomaterials; 9. Infrastructure of the biomaterials industry.
Show moreThis groundbreaking single-authored textbook equips students with everything they need to know to truly understand the hugely topical field of biomaterials science, including essential background on the clinical necessity of biomaterials, relevant concepts in biology and materials science, comprehensive and up-to-date coverage of all existing clinical and experimental biomaterials, and the fundamental principles of biocompatibility. It features extensive case studies interweaved with theory, from a wide range of clinical disciplines, equipping students with a practical understanding of the phenomena and mechanisms of biomaterials performance; a whole chapter dedicated to the biomaterials industry itself, including guidance on regulations, standards and guidelines, litigation, and ethical issues to prepare students for industry; informative glossaries of key terms, engaging end-of-chapter exercises and up-to-date lists of recommended reading. Drawing on the author's forty years' experience in biomaterials, this is an indispensable resource for students studying these lifesaving technological advances.
David Williams is a Professor at the Wake Forest Institute for Regenerative Medicine, North Carolina, with over forty years' experience in biomaterials science. He is the Editor-in-Chief of the international journal Biomaterials, President of the Tissue Engineering and Regenerative Medicine International Society, TERMIS, and a former Director of the UK Centre for Tissue Engineering, where he is now an Emeritus Professor. In addition to these responsibilities he is a Visiting Professor of the Christiaan Barnard Memorial Hospital, Cape Town, and has travelled extensively to promote excellence in scientific research and writing. He is a Fellow of the Royal Academy of Engineering, and has received numerous awards, including the 2012 Acta Biomaterialia Gold Medal.
1. The clinical necessity of biomaterials in the twenty-first century; 2. Essential materials science; 3. Biocompatibility pathways; 4. Implantable medical devices and artificial organs; 5. Regenerative medicine and tissue engineering; 6. Drug and gene delivery; 7. Imaging and diagnostic systems; 8. Contemporary and future biomaterials; 9. Infrastructure of the biomaterials industry.
Show more1. The clinical necessity of biomaterials in the twenty-first century; 2. Essential materials science; 3. Biocompatibility pathways; 4. Implantable medical devices and artificial organs; 5. Regenerative medicine and tissue engineering; 6. Drug and gene delivery; 7. Imaging and diagnostic systems; 8. Contemporary and future biomaterials; 9. Infrastructure of the biomaterials industry.
This groundbreaking single-authored textbook equips students with everything they need to know about biomaterials science.
David Williams is a Professor at the Wake Forest Institute for Regenerative Medicine, North Carolina, with over forty years' experience in biomaterials science. He is the Editor-in-Chief of the international journal Biomaterials, President of the Tissue Engineering and Regenerative Medicine International Society, TERMIS, and a former Director of the UK Centre for Tissue Engineering, where he is now an Emeritus Professor. In addition to these responsibilities he is a Visiting Professor of the Christiaan Barnard Memorial Hospital, Cape Town, and has travelled extensively to promote excellence in scientific research and writing. He is a Fellow of the Royal Academy of Engineering, and has received numerous awards, including the 2012 Acta Biomaterialia Gold Medal.
'This is the long overdue single-author compendium students,
scientists and clinicians were waiting for. Anyone expecting a dry
scientific compilation will be pleasantly surprised by the
wonderfully lively style in which Professor Williams takes the
reader on an exciting journey into the world of modern biomaterials
and the opportunities it offers to patients. In a field long
plagued by self-sustained paradigms, wrong models, and wrong
questions, this book boldly introduces each chapter on the basis of
true clinical needs, taking the captivated reader into the deepest
depths of materials science and biology and eventually leaving him
in a position where his own understanding and judgment has
undergone a quantum leap.' Peter Zilla, University of Cape Town
'This revolutionary book provides a coherent synthesis of the
entire field of biomaterials, from the underlying sciences to its
practical applications. The book is the culmination of thought from
one of the leading pioneers in the field, David F. Williams, who
has been active for over 45 years, and is able to bring together
not only the importance of the subject matter, but also its
historical perspective and future trends. With a strategic focus of
thought, this unique text is a seminal contribution that provides
an invaluable and thorough resource for anyone interested in the
biomaterials field, not just for students, but also for scientists,
and government and industry personnel.' Anthony Atala, Wake Forest
University School of Medicine
'This book distils the wide-ranging field of biomaterials down to
critical topics, and presents them in an accessible and
user-friendly way. In writing the book, the author applies his
innovative ideas, vast knowledge and rich experience to adroitly
tackle the challenge of 'less is more' in processing a wealth of
subject matter, placing a special focus on dynamic interactions
between various biomaterials with complex biological systems, and
translation of tissue engineering products to the clinic. Another
valuable feature of this book is the pedagogical implications
contained in each topic, which begins with a clear, simple diagram
to introduce the reader to the core information, and ends with a
number of questions to help the reader to integrate basic concepts
into practice. Accordingly, this book provides a great reference
for graduate students, researchers and doctors specializing in
biomaterials science. Such empowerment will inevitably lead to
advancing the state of the art in the field.' Xiaosong Gu, Nantong
University
'David Williams is one of the leading international authorities in
biomaterials. Drawing on his vast multidisciplinary experience in
the field, Professor Williams presents in this attractive textbook
not only a comprehensive view of biomaterials in their various
facets, but also innovative ideas, along with the clarity of
thought and precision of expression that those who know him well
have come to expect of him. Although written primarily for students
in biomaterials curricula, I see this book as 'a must' for the
personal and institutional library.' C. James Kirkpatrick, Johannes
Gutenberg Universität Mainz
'This is an extraordinary, impressively thorough, reference source
and textbook. David Williams has a rare knack for clear
communication. He draws on a unique combination of outstanding
knowledge, remarkable experience, and a rare appreciation of the
key concepts. This book is an absolutely essential, superbly
comprehensive, and valuable resource for anyone who wants to truly
understand the field of biomaterials.' Tony Weiss, University of
Sydney
'Williams' Essential Biomaterials Science combines comprehensive
scope, single-authored consistency, and contemporary translational
practicality in this novel textbook on biomaterials. The book
clusters detailed considerations of materials, pathobiology,
applications, regenerative therapeutics, and considerations of
commercialization and clinical implementation, with an overriding
focus on biocompatibility and concepts of biomaterial-tissue
interactions, a key theme of Williams' many contributions to and
leadership in this field. Well-illustrated, particularly with
conceptual graphics, well-referenced with suggested readings, and
with end-of-chapter questions, the book is most likely to be most
useful to university students at an advanced undergraduate or
graduate level, and nicely complements other available references
in adding to the richness and usefulness of literature in the
field.' Frederick Schoen, Brigham and Women's Hospital, Harvard
Medical School
'It is a remarkable achievement for any one individual, even if
that individual is David Williams, to construct such an
accomplished and authoritative text. Based on a lifetime spent in
the field, this book is comprehensive, thought-provoking, and
forward-looking, and is beautifully written and illustrated. While
intended, primarily, as a student text, it is certain that there
will be biocompatibility between this work and academics,
clinicians, regulators and industry practitioners alike, and it is
destined to become a definitive biomaterials science text.' Keith
McLean, CSIRO
'This book provides the reader with the most up-to-date information
on the ground-breaking revolutions in biomaterials sciences, and
huge application potentials to overcome the most acute clinical
challenges in the 21st century. Reading this book is an academic
enjoyment!' Yan Li, Zhongnan Hospital of Wuhan University
'As the advancement of medical science curing various diseases, the
role of biomaterials applied to medicine is recognized to be larger
in recent years. Almost every week, new biomaterials are announced
and launched in the market, and for keeping the high development
speed of biomaterials for according to strong demands from medical
science, many biomaterial scientists and engineers should be
educated. At this moment, this single-authored textbook is just
published. This book is composed of several chapters containing
important information with many beautiful illustrations and
photographs, which help students to understand biomaterials from
very basic to near clinical applications. As one of the unique
points of this book, each chapter has a brief of glossary of
biological and medical terms, which may be unfamiliar for
students.' Teruo Okano, Tokyo Women's Medical University
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