Preface

Preface to the First Edition

UNIT 1: GENERAL PRINCIPLES OF TOXICOLOGY

1. History and Scope of ToxicologyMichael A. Gallo

2. Principles of ToxicologyDavid L. Eaton and Steven G. Gilbert

3. Mechanisms of ToxicityZoltán Gregus

4. Risk AssessmentElaine M. Faustman and Gilbert S. Omenn

UNIT 2: DISPOSITION OF TOXICANTS

5. Absorption, Distribution, and Excretion of ToxicantsLois D. Lehman-McKeeman

6. Biotransformation of ZenobioticsAndrew Parkinson, and Brian Ogilvie

7. ToxicokineticsDanny D. Shen

UNIT 3: NON-ORGAN-DIRECTED TOXICITY

8. Chemical Carcinogens James E. Klaunig, and Lisa M. Kamendulis

9. Genetic ToxicologyR. Julian Preston, and George R. Hoffmann

10. Developmental ToxicologyJohn M. Rogers, and Robert J. Kavlock

UNIT 4: TARGET ORGAN TOXICITY

11. Toxic Responses of the BloodJohn C. Bloom, and John T. Brandt

12. Toxic Responses of the Immune SystemNorbert E. Kaminski, Barbara L. Faubert Kaplan, and Michael P. Holsapple

13. CHAPTER TO COME

14. Toxic Responses of the KidneyRick G. Schnellmann

15. Toxic Responses of the Respiratory SystemHanspeter R. Witschi, Kent E. Pinkerton, Laura S. Van Winkle, and Jerold A. Last

16. Toxic Responses of the Nervous SystemVirginia C. Moser, Michael Aschner, Rudy J. Richardson, and Martin A. Philbert

17. Toxic Responses of the Ocular and Visual SystemDonald A. Fox and William K. Boyes

18. Toxic Responses of the Heart and Vascular SystemY. James Kang, DVM, PhD, FATS

19. Toxic Responses of the SkinRobert H. Rice, and Theodora M. Mauro

20. CHAPTER TO COME

21. Toxic Responses of the Endocrine SystemCharles C. Capen

UNIT 5: TOXIC AGENTS

22. Toxic Effects of PesticidesLuis G. Costa

23. Toxic Effects of MetalsJie Liu, Robert A. Goyer, and Michael P. Waalkes

24. Toxic Effects of Solvents and VaporsJames V. Bruckner, Satheesh S. Anand, and D. Alan Warren

25. Health Effects of Radiation and Radioactive MaterialsNaomi H. Harley

26. Properties and Toxicities of Animal VenomsJohn B. Watkins, III

27. Toxic Effects of PlantsStata Norton

UNIT 6: ENVIRONMENTAL TOXICOLOGY

28. Air PollutionDaniel L. Costa

29. EcotoxicologyRichard T. Di Giulio, and Michael C. Newman

UNIT 7: APPLICATIONS OF TOXICOLOGY

30. Food ToxicologyFrank N. Kotsonis, and George A. Burdock

31. CHAPTER TO COME

32. Clinical ToxicologyLouis R. Cantilena Jr.

33. Occupational ToxicologyPeter S. Thorne

Index

Curtis D. Klaassen, Ph.D., is Professor of Pharmacology, Toxicology, and Therapeutics at the Unviersity of Kansas Medical Center, Kansas City, KS.