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Cancer: Oxidative Stress and Dietary Antioxidants, Second Edition, covers the science of oxidative stress in cancer and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor-mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component. Other sections cover new organ site tumors—skin and liver cancer, the role of polymorphisms, cytochrome p450s, COX gene, fatty acids, apoptosis, T cells and mitochondria, prevention/protection with anthocyanins, esculetin, nanoparticles, and more.
This book is a valuable resource for cancer researchers, oncologists, nutritionists and other members of the biomedical field who are interested in enhancing treatment outcome, improving the quality of life of patients, and developing new treatments in the fight against cancer.
Cancer: Oxidative Stress and Dietary Antioxidants, Second Edition, covers the science of oxidative stress in cancer and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor-mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component. Other sections cover new organ site tumors—skin and liver cancer, the role of polymorphisms, cytochrome p450s, COX gene, fatty acids, apoptosis, T cells and mitochondria, prevention/protection with anthocyanins, esculetin, nanoparticles, and more.
This book is a valuable resource for cancer researchers, oncologists, nutritionists and other members of the biomedical field who are interested in enhancing treatment outcome, improving the quality of life of patients, and developing new treatments in the fight against cancer.
Section 1 Oxidative Stress and Cancer1. Paraoxonases, Oxidative
stress and Breast cancer2. Oxidative stress and prostate cancer3.
Oxidative stress in lung cancer4. Endogenous antioxidants in the
prognosis and treatment of lung cancer5. Oxidative stress in
stomach cancer6. Oxidative stress and oral cavity cancer7.
Oxidative stress, Epigenetics and Bladder Cancer8. Linking
oxidative stress and ovarian cancers9. Oxidative stress in viral
carcinogenesis10. Polymorphisms, antioxidant genes and cancer11.
Interlinking high fat diets, oxidative stress, heart and
carcinogenesis12. Maternal nutrition, antioxidant defenses and
tumor-bearing offspring13. Inflammation and oxidatively induced DNA
damage: A synergy leading to cancer development14. Ferroptosis,
Free radicals and cancer15. Nrf2, YAP antioxidant potential and
cancer16. Cancer, NF kappa B,and oxidative stress-dependent
phenotypes17. 8-hydroxydeoxyguanosine and diabetic cancer
patients
Section 2. Antioxidants and Cancer18. Molecular Approaches Toward
Targeted Cancer Therapy with Some Food Plant Products: On the Role
of Antioxidants and Immune Microenvironment19. Prostate Cancer and
food-based antioxidants in India as plausible therapeutics20.
Linking non-enzymatic antioxidants in the diet and colorectal
cancer21. Fruit and vegetables juices and breast cancer22. N-3
fatty acids and oxidative stress in cancer23. Statins, cancer and
oxidative stress24. Role of anthocyanins in oxidative stress and
the prevention of cancer in the digestive system25. Caffeic Acid
targets metabolism of cervical squamous cell carcinoma26. Caffeic
acid, oxidative balance and melanoma cancer cells27. Oxidative
stress and cancer: Antioxidative role of Ayurvedic plants28.
Polyphenol chlorogenic acid, antioxidant profile and breast
cancer29. Cinnamomum cassia, apoptosis, transcription 3
inactivation and reactive oxygen species in cancer studies30. Cocoa
and anti- oxidative stress actions in colonic cancer31. Croton
gratissimus, cancer and antioxidant activities32. Curcumin,
oxidative stress and breast cancer33. Curcumin analogs, oxidative
stress and prostate cancer34. Fern extract, oxidative stress and
skin cancer35. Lycium barbarum (Goji berry), human breast cancer
and antioxidant profile36. Manuka honey, oxidative stress,
5-fluorouracil usage and colon cancer cells37. Piplartine
(piperlongumine), oxidative stress and use in cancer38. Antioxidant
pleurotus ostreatus (Jacq.) P. Kumm and lymphoid cancer cells39.
Skin cancer, polyphenols and oxidative stress40. Pterostilbene and
cancer chemoprevention41. Resveratrol, reactive oxygen species and
mesothelioma42. Exercise, Selenium and Cancer Cells43. Silybum
marianum, antioxidant activity and cancer patients44. Terminalia
ferdinandiana Exell. Fruit extracts, antioxidant profile,
proliferation and cancer45. Uncaria tomentosa: a promising source
of therapeutic agent for prevention and treatment of oxidative
stress and cancer46. Pharmacologic vitamin C and use in cancer47.
Antioxidant vitamins and genetic polymorphisms in breast cancer48.
Antioxidant vitamins in acute lymphoblastic leukemia
Section 3. Online Resources49. Resources
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books. Dr. Patel is a Reader at the University of Westminster. After completing his PhD at King’s College London, he continued his research experience by undertaking his post-doctoral studies in the laboratory of Professor Cunningham in the Department of Biochemistry at the Wake Forest University School of Medicine, (Winston-Salem, NC, USA). This extensive project involved investigating mechanisms of hepatic mitochondrial ribosome dysfunction in alcoholic liver disease (ALD) using biophysical and proteomic techniques. These studies have led to new avenues in determining the pathology of ALD. His teaching areas at both post-graduate and undergraduate levels include clinical biochemistry, investigative pathology and laboratory investigation.
"This book is a valuable resource for cancer researchers, oncologists, nutritionists and other members of the biomedical field who are interested in enhancing treatment outcome, improving the quality of life of patients, and developing new treatments in the fight against cancer." --Anticancer Research
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