These questions and more, are answered by a distinguished team of nearly 40 specialists in the field who present the latest epidemiological, genetic, molecular, cellular, and diagnostic research findings in lung cancer research and their applications in patient management. "Biology of Lung Cancer" discusses available in vivo and in vitro models and their appropriate uses in specific studies; highlights recent research on mechanisms of lung cancer in addition to potential future patient management targets; explores mechanisms of resistance to treatment and reveals current and developing strategies in chemotherapy and gene therapy; shows how novel data on the progression of premalignant molecular and cellular properties can be applied towards early definitive diagnosis; considers the inheritance of genes that play pivotal roles in carcinogen activation and deactivation and more! Complemented with nearly 2500 bibliographic citations, drawings, photographs, and x-rays, this landmark reference is fundamental reading for pulmonologists, oncologists, physiologists, pathologists, cancer researchers, cardiothoracic surgeons, pharmacologists, biochemists, biophysicists, geneticists, epidemiologists, radiation oncologists, neurobiologists, and graduate and medical school students in these disciplines.
These questions and more, are answered by a distinguished team of nearly 40 specialists in the field who present the latest epidemiological, genetic, molecular, cellular, and diagnostic research findings in lung cancer research and their applications in patient management. "Biology of Lung Cancer" discusses available in vivo and in vitro models and their appropriate uses in specific studies; highlights recent research on mechanisms of lung cancer in addition to potential future patient management targets; explores mechanisms of resistance to treatment and reveals current and developing strategies in chemotherapy and gene therapy; shows how novel data on the progression of premalignant molecular and cellular properties can be applied towards early definitive diagnosis; considers the inheritance of genes that play pivotal roles in carcinogen activation and deactivation and more! Complemented with nearly 2500 bibliographic citations, drawings, photographs, and x-rays, this landmark reference is fundamental reading for pulmonologists, oncologists, physiologists, pathologists, cancer researchers, cardiothoracic surgeons, pharmacologists, biochemists, biophysicists, geneticists, epidemiologists, radiation oncologists, neurobiologists, and graduate and medical school students in these disciplines.
Overview of the Biology of Lung Cancer, Madeleine A. Kane and Paul
A. Bunn, Jr.
Epidemiology of Lung Cancer, Anthony J. Alberg and Jonathan M.
Samet
Genetics of Lung Cancer, Joan E. Bailey-Wilson, Jonathan S. Wiest,
Geno Saccomanno, and Marshall W. Anderson
Carcinogenesis and Lung Cancer Prevention, Gail L. Shaw
New Pharmacological Treatments for Lung Cancer, Karen Kelly
Gene Therapy of Lung Cancer, David S. Schrump and Jack A. Roth
Mechanisms of Drug Resistance in Lung Cancer, N. H. Mulder, R. C.
A. M. van Waardenburg, and E. G. E. de Vries
Preclinical Models of Lung Cancer: Cultured Cells and Organ
Culture, Ming-Sound Tsao and Jean Viallet
Preclinical Models of Lung Cancer, John R. Benfield, Hildegard M.
Schuller, Alvin M. Malkinson, and Mary E. Sunday
Alterations in Cell Cycle Control in Lung Cancer, Robert A.
Sclafani, Irene E. Schauer, and Thomas A. Langan
Growth Factors and Receptors in Non-Small Cell Lung Cancer, Jill M.
Siegfried, Autumn Gaither Davis, Christopher T. Gubish, Mary Ann A.
Demichele, and Praveena Singh-Kaw
Growth Factors and Receptors in Small Cell Lung Cancer, Terry W.
Moody
Signal Transduction Abnormalities in Lung Cancer, Lynn E. Heasley
and Gary L. Johnson
Activating Oncogenes in Lung Cancer, Mack Mabry
Protein Kinase C Modulation by Tobacco Tumor Promoters, Rayudu
Gopalakrishna, Usha Gundimeda, and Zhen-hai Chen
Effects of Tobacco Smoke Constituents on Lung Cells, Hildegard M.
Schuller
Chromosome 3p Loss in Lung Cancer, Robert M. Gemmill and Harry A.
Drabkin
Topography of Preneoplasia: Morphology and Markers, Ilona
Linnoila
New Molecular and Cellular Approaches to Lung Cancer Detection,
Wilbur A. Franklin
Perspectives on Lung Cancer for the Twenty-First Century: Impact of
Cellular and Molecular Biology, Madeleine A. Kane and Paul A. Bunn,
Jr.
"a good balance of information about basic cellular and molecular biology as well as their potential applications, highlighted by the chapters on preneoplasia and lung cancer detection. This makes [the book] attractive to both scientists working in basic science as well as clinicians with research interests. "-Australian Cancer Society
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